Julian Bell transports us to the spirited Rome of the 1600s, where Elsheimer and other young Northern immigrants – notably his friend Peter Paul Rubens – swapped pictorial and poetic reference points. Focusing on some of Elsheimer's most haunting compositions, Bell drives at the anxieties that underlie them – a puzzling over existential questions that still have relevance today. Traditional themes for imagery are expressed with fresh urgency, most of all in Elsheimer's final painting, a vision of the night sky of unprecedented poetic power that was completed at a time of ferment in astronomy.

Circulated through prints, Elsheimer’s pictorial inventions affected imaginations as disparate as Rembrandt, Lorrain and Poussin. They even reached artists in Mughal India, whose equally impassioned miniatures expand our sense of what 'nature' might be. As we home in on artworks of microscopic finesse, the whole of the 17th-century globe and its perplexities starts to open out around us.